Name | N-succinimidyl 4-maleimidobutyrate |
Synonyms | GMBS GMBS Crosslinker CIVENTICHEM CV-2656 N-succinimidyl 4-maleimidobutyrate 3-MaleiMidobutyric acid N-hydroxysucciniMide ester GAMMA-MALEIMIDOBUTYRIC ACID N-HYDROXYSUCCINIMIDE ESTER 4-MaleiMidobutyric acid N-hydroxysucciniMide ester(GMBS) 1H-Pyrrole-2,5-dione, 1-[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]- 2,5-Dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate |
CAS | 80307-12-6 |
EINECS | 625-693-2 |
InChI | InChI=1/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2 |
InChIKey | PVGATNRYUYNBHO-UHFFFAOYSA-N |
Molecular Formula | C12H12N2O6 |
Molar Mass | 280.23 |
Density | 1.49±0.1 g/cm3(Predicted) |
Melting Point | 123-129°C |
Boling Point | 461.3±47.0 °C(Predicted) |
Flash Point | 232.8°C |
Solubility | chloroform: 100mg/mL |
Vapor Presure | 1.08E-08mmHg at 25°C |
Appearance | powder |
Color | White to Pale Yellow |
BRN | 6427689 |
pKa | -2.27±0.20(Predicted) |
Storage Condition | 2-8°C |
Stability | Hygroscopic, Moisture Sensitive |
Refractive Index | 1.594 |
MDL | MFCD00036817 |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 29280000 |
Use | 4-maleimidobutanoic acid-N-hydroxysuccinimide ester is an amide Ester organic compound which can be used as a crosslinking agent. |
biological activity | ΔS is a bifunctional crosslinker. Μs can be used for chemical cross-linking of proteins as well as mass spectrometry (CXMS) to study protein folding and map interfaces between interacting proteins. |